Agrochemical company BASF has received Irish authorisation for a new fungicide active ingredient, Revysol. Revysol (common name mefentrifluconazole) is an isopropanol-azole and is the first of its class to be introduced to the market.

Two products containing the new active ingredient, Lentyma and Revystar XL, have been cleared for use in wheat, barley and oats, and offer strong broad-spectrum activity to a host of key cereal diseases.

Revysol active ingredient with Isopropanol unit in orange.

The molecular structure of the new azole is said to unique due its isopropanol unit. This unit allows for structural flexibility, meaning that the molecule can form flexible conformations to adapt into the binding pocket of the target fungal enzyme.

The Revysol active ingredient is capable of flexing due to the Isopropanol unit.

On average, Revysol will bind 100 times more powerfully than conventional azoles. This results in stronger efficacy to maximise fungicide effect.

Revysol has both strong curative and protectant activity will be an important new tool for disease and resistance management.

Disease control

Revysol shows the same activity against septoria as older azoles like epoxiconazole and prothioconazole before their efficacy against the disease declined.

Revysol also has strong broad-spectrum efficacy against other key cereal diseases such as brown and yellow rust and mildew. On ramularia in barley, Revysol is the second best active for the disease after chlorothalonil.

A new azole product will be available this spring and is expected to contain the new azole Revysol along with other actives. It will not as a straight product to protect against disease resistance building up.

BASF’s David Leahy says: “The timing for this authorisation comes at a vital time for growers, given the loss of chlorothalonil (CTL), the rise in resistance and the decline in efficacy of the conventional triazoles, prothioconazole and epoxiconazole.

“Revysol shows outstanding field performance in both curative and protectant situations, delivering a new level of disease control compared to existing azoles,” added David.

Revysol will be officially launched in Ireland on 6 February 2020.

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